Category Archives: Gene therapy

A safer micro-RNA Guided Gene Therapy

Researchers from Dankook University in Korea have found a new method of introducing transgenes with therapeutic purposes. The study, published in Nucleic Acid Therapeutics, describes how targeting the passenger strand of a micro-RNA (miRNA) linked to the transgene is better than targeting the guide strand. The new system avoids the derregulated expression that the canonical method causes in the miRNA targeted endogenous genes. miRNAs are short oligonucleotides that do not code for […]