CRISPR/Cas9 Delivery System Reduces Chronic Anxiety in Mice
Newly Discovered CRISPR/Cas9 Delivery System Takes Genome Editing Beyond the Blood-Brain Barrier
Humans Found to Hold Immunity to CRISPR-Cas9
CRISPR-Cas9, the 21st Century’s most promising genetic modification tool has shown to be unusable in humans, thanks to adaptive immunity already present in human beings. In a pre-print paper published […]
CRISPR as a Recorder of Molecular Activity
Researchers from Harvard University have succesfully proved that CRISPR can work as a recorder of molecular events. Synthetic DNA molecules introduced in bacteria over a defined timespan were integrated by the […]
Anti-CRISPR Proteins from Prophages Discovered in Proteobacterial Genomes
Researchers from the University of Toronto and the University of Otago have discovered five new proteins that block the bacterial CRISPR/Cas immune system. The anti-CRISPR proteins are encoded in genes belonging to […]
CRISPR/Cpf1 Edits Mice Embryos Without Off-Target Effects
Researchers at the IBS Center for Genome Editing in South Korea have successfully created mutant mice using CRISPR/Cpf1. The alternative to the well-known CRISPR/Cas9 system can edit genomes with exquisite precision and […]
New CRISPR Nuclease Cuts Both DNA and RNA
CRISPR/Cas9 co-discoverer Emmanuelle Charpentier and collaborators from Germany and Sweden have found that Cas nuclease Cpf1 cleaves DNA and RNA. Cpf1 cuts a precursor of crRNA to produce the mature form; it requires only […]
CRISPRainbow Allows to Tag Seven Genomic Loci Simultaneously
Researchers from University of Massachusetts Medical School have developed a new technique to simultaneously track up to seven genomic locations in live cells. The CRISPRainbow system is based on the genomic […]
HIV Beats CRISPR in First Round, HIV 1 | CRISPR 0
Scientists have come to the surprising realization of HIV’s immense ability to evolve resistance to drugs and now even gene editing using CRISPR. Researchers at McGill University in Montreal have […]