Category Archives: Structural biology

iproteos

Teresa Tarragó: “Crowdfunding is a Source of Financing for Early Stage Biotechs”

Labcritics was at Iproteos’ facilities talking to Teresa Tarragó, CEO and co-founder of this innovative company. Iproteos combines computational chemistry with modern synthesis methods to generate peptidomimetics with pharmacological activity against diseases such as schizophrenia. We had the opportunity to know about the possibilities of crowdfunding for biotech projects and the technology used in their laboratory. […]

Bacterial Hair Conducts Electricity and Could Be Used in Bioelectronic Devices

Scientists from the University of Massachusetts at Amherst, Holy Cross, and Brookhaven National Laboratory have discovered that the filaments present in the surface of Geobacter bacteria have conductive properties comparable to those of copper. The finding, published in the journal mBio, could accelerate the introduction of biological material in nanoscale electronical devices. In general, proteins are […]

Cryoem_groel

Cryo-Electron Microscopy Is the Method of the Year 2015

Nature Methods has named Cryo-Electron Microscopy the method of the year 2015. This structural technique, which was always a step behind nuclear magnetic resonance (NMR) spectroscopy and X-ray crystallography, is now capable of near-atomic resolution thanks to important technical advances. Most protein structures have traditionally been solved by X-ray crystallography, but some proteins are not crystallizable. The common […]

single protein hologram structure

Electron Holography Microscope Obtains First Image of a Single Protein

  Researchers from the University of Zurich have obtained the first image ever of a single protein. The molecule was fixed on a graphene sheet and imaged with an electron holographic microscope. By emitting low-energy electrons, this technique acquired images without damaging the sample, and the thinness of graphene allowed electrons to pass through it and […]

Salinas

Gabriel Ortega: “How Do Halophiles Endure Extreme Salinity?”

The slow but unstoppable progress of evolution has enabled, step by step, mutation after mutation, the conquest of virtually all ecosystems on Earth. Even in those places where conditions are far from “standard”, where the presence of organisms seems unthinkable, life has found its way. These small conquerors are called extremophiles. Thus we find thermophilic organisms that […]

SOD1 Trimeric Species Causes Neuron Death and ALS

Researchers from the University of North Carolina School of Medicine have solved the structure of a toxic protein aggregate that causes Amiotrophic Lateral Sclerosis (ALS). Mutants of the Cu,Zn superoxide dismutase (SOD1) protein prone to form trimers aggregated and increased neuron death. This is the first experimental evidence of protein aggregates causing the neurodegenerative disease. The study was published […]

The Bucaramanga Giant Who Crossed the Atlantic for Science

Jhon Alex Rodriguez Buitrago is a Colombian structural biologist who left his country to pursue a scientific career that has already taken him to Spain, Belgium and the Czech Republic. In love with evolution, positivism, Richard Dawkins and biophysical techniques, Jhon Alex talks about his life in the countries with the best beer in the world, strategically chosen […]