Category Archives: Personalized Medicine

CRISPR Kit

Humans Found to Hold Immunity to CRISPR-Cas9

CRISPR-Cas9, the 21st Century’s most promising genetic modification tool has shown to be unusable in humans, thanks to adaptive immunity already present in human beings. In a pre-print paper published by researchers at Stanford University, more than 65 percent of human subjects had antibodies that would fight Cas9 proteins propagation in human beings. More specifically 79% […]

xenopat

Xenopat: Your Tumor in a Mouse

Labcritics visited Xenopat, an innovative company dedicated to the orthotopic implantation of human tumors in mice. This technology allows Xenopat to offer services to companies developing new anticancer drugs and personalized cancer treatments. We had the pleasure of speaking with Dr. Anna Portela, CEO and co-founder, and Dr. Alberto Villanueva, CSO and co-founder. For more […]

Droplet Digital PCR to Measure Tumor Load

Christof Winter from Technische Universität München presented at Analytica the innovative use of droplet digital PCR to measure tumor load by non-invasive means. The technique takes advantage of the cell-free DNA circulating in blood, which is found in higher concentration in cancer patients. Cell-free DNA (cfDNA) is found in blood plasma at concentrations of 10–100 […]

sequencing by synthtesis

A More Precise Nanopore Sequencer Based on Polymer-Tagged Nucleotides

Researchers from Columbia University School of Engineering and Applied Science have developed an advanced real-time, single-molecule nanopore sequencer. In collaboration with Genia Technologies (Roche), Harvard University and the National Institute of Standards and Technology (NIST), the engineers built an electronic DNA sequencer with better resolution than current nanopore devices. The study was published in the journal PNAS. Genome sequencing has allowed […]

Next Generation Sequencing

Study Identifies Individuals Resilient to Severe Genetic Diseases

Researchers from the Icahn School of Medicine at Mount Sinai in New York City have discovered that certain individuals have the ability to survive genetic disorders that usually have severe or lethal consequences. A genetic screen of almost 600000 healthy people identified 13 of them carrying mutations in essential genes. The study has been published in the […]

illumina

Illumina Partners with 4 Biobanks to Genotype Their Collections

Illumina has signed agreements with Vanderbilt University, University of Colorado at Anschutz Medical Campus, Partners HealthCare, and Montreal Heart Institute to genotype their sample collections. Illumina’s technology will initially analyze 200000 samples and combine the obtained genomic data with clinical records to identify the genetic causes of several diseases. Illumina’s sequencing technology, Infinium® Expanded Multi-Ethnic Genotyping Array […]

nanopore diagnostics logo

Nanopore Diagnostics Raises $600000 to Develop the iNDxer

American startup Nanopore Diagnostics has raised $600000 to develop The iNDxer, a device to detect bacterial infections. The money, provided by the Missouri Technology Corporation and other minor investors, will be allocated to conduct clinical trials that will validate the use of the Nanopore Diagnostics’ device by physicians. Nanopore Diagnostics CEO Tom Cohen was mistakenly […]

Nuria

Núria Montserrat: “The Enviroment Is Fundamental for Success”

Labcritics presents an interview with Núria Montserrrat, Junior Group Leader at the Institute for Bioengineering of Catalonia. The talented young woman shares with us her love for research, the college years, the hard -but enjoyable- PhD, the very demanding postdoc with cell-reprogramming phenomenon JC Izpisúa-Belmonte and the current days as independent researcher in the exciting […]