Category Archives: Open Science

New Method Finds Sequences in Minutes Instead of Days

Researchers from Carnegie Mellon University have developed a new database search technique that allows to find DNA sequences in minutes instead of days. The method specializes in finding short reads generated by high-throughput sequencing. The findings were published in the journal Nature Biotechnology. The amount of genetic data with potentially important clinical information is growing very […]

foldscope

Foldscope: A Paper Microscope that Costs $1

A team of researchers from Stanford University has developed a paper microscope that costs one dollar. Foldscope is printed in a sheet of paper and is folded into a functional shape, in a process akin to origami. The device can be easily mass-produced and is aimed to democratize science education and to provide a diagnostic tool […]

PLOS Launches Research-on-Research Section to Increase Transparency

The open-access scientific journal PLOS Biology has launched a section dedicated to research on research. The new section will analyze how research is designed, executed, communicated and evaluated. With this initiative, PLOS aims to regain public confidence in the scientific method after too many cases of irreproducible research. According to several meta-research articles, US$200 billion are spent […]

Mykrobe Predictor Software Identifies Antibiotic Resistance

Researchers from the Wellcome Trust Centre for Human Genetics have developed a new software that predicts antibiotic resistance in bacteria by analyzing their genome. The new tool, called Mykrobe Predictor, was tested in Staphylococcus aureus and Mycobacterium tuberculosis, and the results were similar to common phenotypic tests. The study has been published in Nature Communications. The increase in bacterial […]

Graphene-Based Paper Can Be Programmed to Walk

Engineers from Donghua University in Shanghai have developed a graphene-based paper that can walk and fold itself. Inspired by origami, the nanostructure can be excited by light or heat to change shapes, walk or turn around a corner. The study, published in Science Advances, could find applications in robotics, sensing and the creation of artificial muscles. Origami has influenced […]

International Summit on Human Gene Editing

Scientists from all over the world will gather between today and Thursday in the International Summit on Gene Editing celebrated in Washington, D.C. The experts will discuss the scientific, medical, ethical, and governance consequences of the last advances in human gene editing tools. The main topic will be CRISPR-Cas9, a technique with enormous potential that has raised concerns in the scientific […]

3D Localization of Single Molecules Improved to Nanoscale

University researchers W. E. Moerner, E. Betzig and S. W. Hell won the 2014 Nobel Prize for their development of super-resolution microscopy, a technique that breaks the optical diffraction limit following fluorescent emissions from single molecules. Now, the team led by Professor Moerner at Stanford University has improved this technology, achieving unprecedented accuracy when tracking single molecules in 3D. […]

Hydra Transforms Epithelium Into Rudimentary Nervous System

The freshwater polyp Hydra can regenerate all its body from just a fragment, and survives after losing all its nervous system. Scientists from the University of Geneva (UNIGE) have discovered the mechanism of regeneration: overexpression, in epithelial cells, of genes involved in nervous functions. The results have been published in the journal Philosophical Transactions of the Royal […]