Category Archives: Epigenetics

Genomic Imprinting Can Target Just a Few Cells

Scientists from the University of Utah School of Medicine have discovered that genomic imprinting can be targeted to subregions of tissues or small clusters of cells. The subtlety of this non-canonical imprinting can affect specific behaviours or moods. The finding has been published in Cell Reports. Genomic imprinting is an epigenetic mechanism that silences one of the […]

First Epigenetic Mechanism Involving Histone Tails Solved at Atomic Level

Researchers from the Institute for Research in Biomedicine (IRB Barcelona), the University of Cambridge, and New York University have discovered the structural mechanism of chromatin unfolding by epigenetic modifications. Acetylation of histone tails unfolds chromatin by decreasing tail availability and thus interactions between nucleosomes.The researchers ran computer simulations of nucleosome dynamics and experimentally confirmed the results. […]