Category Archives: Enzymes

telomeres

BioViva’s CEO Claims to Have Longer Telomeres After Gene Therapy

BioViva reported last week that the company’s CEO, Elizabeth Parrish, successfully reversed biological ageing after being treated with the biotech’s therapies. The Seattle-based company confirmed that Parrish reversed 20 years of telomere shortening thanks to an experimental gene therapy. BioViva aims to provide regenerative medicine solutions through gene and cell therapies. The company is involved in several research lines to […]

eSrtA. biofilm regeneration.

New Method to Extend the Lifetime of Implanted Devices

Researchers from Harvard University have developed a biochemical mechanism to extend the time that an implanted medical device can remain functional and not trigger an immune response. In a study published in Nature Communications, the authors engineered an enzyme to make it extremely efficient in replacing the biofilm that coats the devices and prevents unwanted physiological reactions. Medical […]

Targeting Our Gut Microbes Could Cure Arteriosclerosis

Researchers from Cleveland Clinic have discovered that blocking a specific microbiome metabolic pathway can diminish the risk of arteriosclerosis for the host. A compound found in olive oil and red wine interferes with the gut microbiota’s metabolism, lowering the levels of bacterial metabolic by-products that contribute to hardening arteries and increase the risk of cardiovascular diseases. […]

PITCh: An Alternative Use of TALENs and CRISPR/Cas9

Researchers from Hiroshima University have presented a new gene insertion method called Precise Integration into Target Chromosome (PITCh). The method uses existent gene editing technologies more effectively. The study has been published in the journal Nature Protocols. Recent genome editing techniques have allowed researchers an unprecedented capacity for DNA sequence modification at the desired target. Gene insertions and deletions can […]

A Semi-Biological Integrated Circuit Powered by ATP

Engineers from Columbia University (CU) have developed an integrated circuit that uses adenosine triphosphate (ATP), the molecular unit of currency, as a source of energy. The researchers created an artificial system with both biological and artificial, solid-state components. The study was published in the journal Nature Communications. ATP transports chemical energy inside cells, and is […]

Rolling DNA Motor is the Fastest Ever Designed

Researchers from Emory University have developed a nano-robot based on rolling DNA that moves faster than any previously designed DNA motors. The technique, based on DNA-coated spheres that bind to an RNA layer, could find applications in disease diagnostics. The findings were published in Nature Nanotechnology, There are many examples of natural nano-robots in the cells, with […]

crispr-cas9

A Novel Cas9 Recognizes More DNA Targets

Researchers from the Massachussets General Hospital (MGH) have engineered the Cas9 nuclease from Staphylococcus aureus (SaCas9) to recognize more targets. The prokaryote RNA-guided immune system, used as a genome editing tool, can target now a broader range of nucleotide sequences. The study has been published in the journal Nature Biotechnology. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and […]

A Deep-Sea Bacterium Against Climate Change

An organism that lives at the bottom of the ocean could help in the fight against climate change. The bacterium, Thiomicrospira crunogena, lives in extremely hot environments and produces an enzyme -carbonic anhydrase- that can convert carbon dioxide into harmless products. These two characteristics make it a good candidate for industrial use. The study, by researchers […]