Category Archives: Developmental biology

First Visualization of Cancer Spread from its Origin

Researchers from Boston Children’s Hospital have visually followed the emergence and spread of cancer form its first cell to other parts of an animal. The pioneering study, published in the journal Science, will help scientists understand cancer development and find new treatments. Some cells that present typical cancer mutations do not behave like cancer cells. […]

GFP tagged naive stem cells

A New Method to Perpetuate Human Stem Cell Cultures

An international team of researchers from several institutions led by the University of Bath have developed a new method to detect and preserve human stem cells in culture. The new technique keeps active a genetic sequence that is always found active in naive stem cells. The study was published in the journal Nature Protocols. Naive embryonic stem cells […]

New Cell Line Produces Critical Component for Organoid Cultures

Trevigen has released a cell line that produces a fundamental element for propagating organoid cultures. The HA-R-Spondin-Fc293T cells can be used to obtain Roof plate specific Spondin-1 (R-Spondin 1 or RSPO1) as well as RSPO1 media. RSPO1 is critical for the support and proliferation of organoid progenitor stem cells from mice and humans. RSPO1 has been succesfully used to produce stem […]

Nuria

Núria Montserrat: “The Enviroment Is Fundamental for Success”

Labcritics presents an interview with Núria Montserrrat, Junior Group Leader at the Institute for Bioengineering of Catalonia. The talented young woman shares with us her love for research, the college years, the hard -but enjoyable- PhD, the very demanding postdoc with cell-reprogramming phenomenon JC Izpisúa-Belmonte and the current days as independent researcher in the exciting […]

Functional Liver Cells Cultured in the Lab

An international team of researchers led by The Hebrew University of Jerusalem has developed a technique to grow functional hepatocytes in vitro. The cultured cells will allow to perform drug screenings and test them on liver cell lines with specific genetic diseases, as well as to create artificial-biological livers for patients waiting for a transplant. The study […]

Hydra Transforms Epithelium Into Rudimentary Nervous System

The freshwater polyp Hydra can regenerate all its body from just a fragment, and survives after losing all its nervous system. Scientists from the University of Geneva (UNIGE) have discovered the mechanism of regeneration: overexpression, in epithelial cells, of genes involved in nervous functions. The results have been published in the journal Philosophical Transactions of the Royal […]

3D Printing is not Innocuous for Health

Researchers from the University of California, Riverside have discovered that the material in some 3D printed objects is surprisingly harmful to living things. The finding happened unexpectedly when a team member designed and used 3D printed objects for her research with zebrafish embryos, which died shortly after being in contact with the objects. The study […]

3D printing of embryonic stem cells in building blocks

  A new 3D printing method allows to obtain regular blocks of embyonic stem cells (ESCs) that could be used to build larger structures like tissues or organs. The researchers from Tsinghua University in Beijing and Drexel University in Philadelphia obtained uniform and homogeneous embryoid body structures that can facilitate further tissue growth. The study was published in the […]